环硅酸锆钠治疗慢性肾脏病患者高钾血症的疗效及对血清钾离子浓度的影响

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中图分类号：R692.5 文献标识码：A

DOI：10.3969/j.issn.1006-1959.2025.21.024 文章编号：1006-1959（2025）21-0115-04

Abstract：OjectiTvestgateacofocoosiceiraentfhpekeinatitsihcidy disease and its effctonserum potassium ionconcentration.MethodsA total of62 patients with CKDadmitted to Ji′ anFirst People's Hospital from June2022toMay4ereseleedstheseahjectsAcodingtoteandomumbertableethothyeredividedintodyoud controlgroupiaichooloastraediiofkalodietated thestudygroupastreatedwithsodumzircomycloslicateowderotebasisoftheontrolgoup.Thetotalefectiveateoftreatmnt electroteed anddversereacoiootosestialcosiatoedteoosl effective rate of treatment in the study group was higher than that in the control group（ P <0.05）.After treatment，the blood potassium index of the study group was lower than that of the control group（ P<0.05 ），and there was no significant difference in other indexes between the two groups （P>0.05） ： Thelevels ofserum creatinineand urea nitrogen in the study group were lower than those in thecontrol group（ P<0.05） .There was no significant difference in the incidence of adverse reactions between the two groups（ P>0.05 .Conclusion The clinical efficacy of sodium zirconiumcyclosilicate inthetreatmentofhyperkaleaipatientswithoicidneydiseaseisefitehichanduceteonentratiooferumotaio improvetherenal functionofpatients，and has high safety.Itisworthyof clinical application.

KeyWords：Sodium zirconiumcyclosilicate; Chronic kidney disease;Hyperkalemia; Serum potassium ionconcentration

慢性肾脏病（chronickidneydiseases，CKD）是危害人类健康的重大疾病，全球CKD患病率在 8% 216%11 。（剩余5430字）