中性粒细胞绝对值计数与血清白蛋白比值对中晚期食管鳞状细胞癌术后患者预后的作用

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中图分类号：R735 文献标识码：A DOI：10.3969/j.issn.1006-1959.2025.12.013

文章编号：1006-1959（2025）12-0065-06

Role of Neutrophil-to-AlbuminRatio inPredicting PrognosisofPatientswithAdvanced Esophageal Squamous Cell Carcinoma After Surgery

ZHAOJiqi，ZHOUMengxi1，LYUYinl，DENGJiaying2，XULei'，DONGYaqin1，ZHULiyang，WANGYichun’，KANGei （1.DepartmentofadiatioOncolgytheirstAfiatedHospitalofAnuidicalUivesityHefeiO，Anin; 2.Department of Radiation，Fudan University Shanghai Cancer Center，Shanghai 2Ooo32， China）

Abstract：ObjetieTevauatetherogosicaluefpreoperativepperalblodeutrophiltoabmiatio（NAR）ipatintswith esophagealsasellrocalgeeJatar4titsioeall carcinomafedicalesetionfrothFstAfliatedHspitalofAnuMedicalUniversiynd6patientsihesoagealuaocel carcinomaafteradicalresetonfromFudanUniversityShanghaiCancerCenterwereselecedassubjectsTheotialutoffvalueofNRws analyzedby X-Tile softwareand divided into low score group （NAR <0 .1） and high score group （NAR≥O.1）.The clinical data of the two groups were compared，ndhgostcoeroudsodeleaplaeeededteald testwasefletei sungical procedure，degree of diffrentiation，tumor locationand TNM stage between the two groups（ P> 0.05）.The median follow-up time was 40 months（range-56months），andthemedianOSwas50O（95%C38.5-61.5）moths.ThemedianOofthelowsoregoupas7（95%C 34.8-79.2）motsntemedanOSoftegoreos25%9oe，ndearuialaesf the low-score group were 85.9 % 60.5% ，49.8%，and 41.0% ，respectively，while the1-，3-， 5- ，and 10-year survival rates of the high-score group were73.4 % ，46.6 % ，36.0%，and23.8 % ，respectively.Coxunivariateanalysisshowedthatgender，smoking history，drinkinghistory，TNMstageand NARwerethegosticctosfOO）.Ftouiaeealodaooade indepedentsctogosplaalisodabsiota Conclusion High NAR （NAR ⩾0.1 ） is an idependent risk factor forOS in patientswith esophageal squamous cell carcinoma.Preoperative NAR is a convenient and efective indicatorfor predicting postoperative survival of esophageal squamous cellcarcinoma.

Keywords：Esophageal squamous cell carcinoma; Neutrophil-to-albumin ratio; TNM stage

食管癌（esophagealcancer）在我国男性和女性中的发病率分别排在第五位和第十位，且随着年龄增长，食管癌发病率呈逐渐上升趋势，并于80＼～84岁达到峰值。（剩余8713字）