运动干预对维持性血液透析病人衰弱影响的Meta分析

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AbstractObjective：Toevaluatetheinterventioneffectofexerciseinterventiononfrailtyinmaintenancehemodialysispatients. Methods：Theliteratureontheefectofexerciseinterventiononthefrailtylevelofmaintenancehemodialysispatientswasretrievedfrom databases suchas PubMed，WebofScience，CNKI，and WanFang Database.The search periodwas from the establishmentof the databasetoNovember224.Literaturesrenng，dataetractionandalityevaluationwereindependentlyconductedbytwoacrs. RevMan5.4softaresdptedretaanalsisResults：Atotalof2rticlesrecudednoling1475patient.esulsfte Meta-analysis show that exercise intervention can effectively improve the frailty state of patients（SMI ）=-1.19，95%CI-1.74-0.64 ， P<0.000 1 ）.The results of subgroup analysis showed that aerobic resistance exercise（SMD ⋅1=-1.30，95%CI-2.19AA-0.41，P=0.004 ） with continuous intervention for l2 weeks（SMD =-1.92，95% CI -2.83--1.01， P=0.000 3），an intervention frequency of 2 or 3 times per week（SMD =-1.13 ， 95% CI -1.80--0.45 ， P<0.000 01 ），and a single exercise duration of ⩽30 minutes（SMD=-1.34， （204号 95% CI—2.21-—0.47， P<0.000 01 ） improved the frailty state of MHD patients better，and the difference was statistically significant. Conclusions：Existing evidence shows exerciseinterventioncanefectivelyimprovedthefrailtystateofMHDpatients.Continuous intervention for12 weeks，2 or 3 times per week，with each session lasting ⩽30 minutes，aerobic resistance exercise may havea better effect in improving the frailty of MHD.

Keywordsexercise intervention; maintenance hemodialysis; frailty; Meta-analysis; evidence-based nursing摘要目的：评价运动干预对维持性血液透析病人衰弱影响的干预效果。（剩余8691字）