8种非药物干预对脑卒中后认知功能障碍疗效的网状Meta分析

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Efficacy of 8 non-drug interventions for post-stroke cognitive impairment： a network Meta-analysis

SONG Daibo LI Mengyao BAI Xue

1.Shandong Provincial Hospital Affiliated to Shandong First Medical University，Shandong 250000 China； 2.Endocrinology and Metabolic Disease Hospital Affiliated to Shandong First Medical University

Corresponding Author  BAI Xue，E⁃mail：sdslicubx@163.com

Abstract Objective：To compare the treatment effects of 8 non⁃drug interventions on patients with post⁃stroke cognitive impairment（PSCI） by network Meta⁃analysis.Methods：The randomized controlled trials（RCTs） of non⁃drug interventions for PSCI were retrieved systematically from PubMed，EMbase，Web of Science，the Cochrane Library，CNKI，WanFang Database，and VIP from the establishment of each database to November 30，2022.After literature screening and information extraction by two researchers independently.The literature was imported into Stata 16 software for analysis.Results：A total of 25 articles were included，involving  1 933 patients.The network Meta⁃analysis results showed that among the 8 intervention programs，7 intervention methods（computer cognitive training，acupuncture，repetitive transcranial magnetic stimulation，transcranial direct current stimulation，hyperbaric oxygen，exercise rehabilitation，and enriched rehabilitation therapy） had better cognitive function recovery effect than the traditional cognitive training.Hyperbaric oxygen had the best treatment effect，followed by repetitive transcranial magnetic stimulation technology.Exercise training had the best treatment effect on the recovery of daily living ability.Conclusions：Hyperbaric oxygen and exercise training can effectively improve the cognitive function and daily living ability of PSCI patients.Nurses may choose which intervention method based on actual conditions in clinical work.

Keywords  stroke；cognitive impairment；non⁃drug intervention；network Meta⁃analysis；hyperbaric oxygen；exercise；evidence⁃based nursing

摘要  目的：通过网状Meta分析比较8种非药物干预对脑卒中后认知功能障碍（PSCI）病人的治疗效果。（剩余10505字）