温阳固涩汤治疗腹泻型肠易激综合征的临床疗效观察

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【摘要】目的：探讨温阳固涩汤治疗腹泻型肠易激综合征患者的临床疗效。方法：在获取研究知情同意的基础上邀请50例腹泻型肠易激综合征患者入组，时间2021年10月—2023年10月，以信封法分成两组，每组25例，对照组给予奥替溴铵治疗，观察组联合温阳固涩汤治疗，用药2周后进行疗效评价。结果：治疗后，相较于对照组，观察组血管活性肠肽、P物质及IBS-SSS评分更低，神经肽Y、IBS-QOL评分及临床治疗总有效率更高（P

【关键词】腹泻型肠易激综合征；温阳固涩汤；胃肠激素；生活质量

Clinical efficacy observation of Wenyang Guse Tang in treating patients with diarrhea type irritable bowel syndrome

ZHAO Yabing

Lintao County Traditional Chinese Medicine Hospital， Dingxi， Gansu 730500， China

【Abstract】Objective：To explore the clinical efficacy of Wenyang Guse Tang in the treatment of patients with diarrhea type irritable bowel syndrome.Methods：On the basis of obtaining informed consent for the study，50 patients with diarrhea type irritable bowel syndrome were invited to participate in the study from October 2021 to October 2023.They were divided into two groups using the envelope method，with25cases in each group.The control group was treated with otilonium bromide，while the observation group was treated with a combination of Wenyang Guse Tang.The therapeutic effect was evaluated after 2 weeks of medication.Results：After treatment，compared with the control group，the vasoactive intestinal peptide，substance P and IBS-SSS scores in the observation group were lower，while neuropeptide Y，IBS-QOL scores and total effective rate of clinical treatment were higher （P

【Key Words】Diarrhea type irritable bowel syndrome； Wenyang Guse Tang； Gastrointestinal hormones； Quality of life

肠易激综合征（IBS）在功能性障碍疾病中十分常见，其总体患病率在1.4%～11.5%之间，患者多数带有腹痛、腹胀、排便习惯改变等症状[1]。（剩余3090字）