补充维生素D对2型糖尿病患者胰岛素抵抗的影响分析

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【摘要】目的：研究并分析补充维生素D在2型糖尿病治疗中的应用。方法：选取82例2型糖尿病患者，于2021年1月—2023年1月在甘肃省靖远县人民医院就诊，将其按照计算机表法进行分组，其中对照组（n=41）实施常规疗法，基于此对实验组实施补充维生素D的疗法，对比两组疗效分析。结果：治疗后，实验组空腹血糖（FPG）、空腹胰岛素（FIns）、餐后2h血糖（2hPG）、胰岛素抵抗指数（HOMA-IR）指标水平均低于治疗前，并且实验组低于对照组，血清25（OH）D3水平高于治疗前，并且实验组高于对照组；血清25（OH）D3≥25mmol/L组FPG、FIns、2hPG、HOMA-IR指标水平明显高于血清25（OH）D3

【关键词】维生素D，2型糖尿病；胰岛素抵抗

Effect of vitamin D supplementation on insulin resistance in patients with type 2 diabetes

RAN Lamei

Jingyuan County People’s Hospital， Gansu Province， Baiyin， Gansu 730600， China

【Abstract】Objective： To study and analyze the application of vitamin D supplementation in the treatment of type 2 diabetes. Methods： 82 patients with type 2 diabetes were selected and treated in the People’s Hospital of Jingyuan County， Gansu Province from January 2021 to January 2023. They were divided into groups according to the computer table method. The control group （n=41） was treated with conventional therapy. Based on this， the experimental group was treated with vitamin D supplementation， and the efficacy of the two groups was compared .Results： After treatment， fasting blood glucose （FPG）， fasting insulin （FIns）， 2h postprandial blood glucose （2hPG） and insulin resistance index （HOMA-IR） indexes of the experimental group were lower than before treatment， and the serum 25（OH）D3 level of the experimental group was higher than before treatment， and the experimental group was higher than the control group. The levels of FPG， FIns， 2hPG and HOMA-IR in serum 25（OH）D3≥25mmol/L group were significantly higher than those in serum 25（OH）D3

【Key Words】Vitamin D， Type 2 diabetes mellitus； Insulin resistance

2型糖尿病是临床中一种以胰岛素抵抗或胰岛素分泌不足为特征的慢性疾病，大多数超重及肥胖人群以胰岛素抵抗为主，且发病率逐年上升，患者长期以高血糖状态生存，会对其生活质量造成不利影响[1]。（剩余2990字）