吲哚菁绿荧光显影技术在口腔鳞状细胞癌手术治疗中的应用进展

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中图分类号]R739.8 [文献标志码]A [doi]10.7518/gjkq.2025027

Progressofresearch on theapplication of indocyanine green fluorescence imaging technologyin thesurgicaltreatment of oral squamous cell carcinoma

MaikeliyaAikepaer',MaimaitituxunTuerdil,2

1.DeptofOraldilacalaogaticugeryirstAfatedHosital(Stotologicaltal) ofXinjiangedicalUniversityUrumqi3o54,China2.InstituteoftomatologyXinjiangUgurAutonomousRegion Urumqi0054,in

Supportedby:NationalNaturalScienceFoundationofChina(82360198)

Correspondence:Maimaitituxun Tuerdi,Email:maimaitituxun@aliyun.com [Abstract]The surgical resection of oral squamouscell carcinoma (OSCC) mostly relieson the experienceof clinicians,suchasvisualexamination,palpation,andpreoperativeimagingexaminationReal-timeandobjectiveintraoperativeevaluationmethodsarealsolacking.Indocyaninegren(ICG)isasafeandpollution-freeorganicfluorescentdyethat accumulatesanddevelopsatalesionunder near-infrared(NIR)fluorescence.This techniquecanbeapplied inthevisualizationof primarytumorsand suroundingbloodvesselsand nerves,sentinel lymph-nodebiopsy,cervical lymphnode dissection,andtheevaluationoffree-flapbloodsupplyfortherepairandreconstructionofOSCC.NIRimaging technology may becomea keylink in theearly diagnosis and precise treatment ofOSCC in the future.This article reviews the application ofICG-NIR in OSCC.

[Keywords] indocyanine green;near infrared fluorescence imaging;oral squamous cellcarcinoma

口腔鳞状细胞癌(oralsquamouscell carcino-ma,OSCC)是口腔颌面部最常见的恶性肿瘤之一,是颌面部重大疾病之一,其治疗以手术切除为主。(剩余13426字)

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