俯卧位通气时长对重症肺炎病人氧合及肠内营养耐受性的影响

打开文本图片集

Effect of prone position ventilation duration on oxygenation and enteral nutrition tolerance in patients with severe pneumonia

Abstract  Objective：To investigate the effect of the duration of prone position ventilation on the safety and effectiveness of early oxygenation and enteral nutrition in patients with severe pneumonia.Methods：90 patients with severe pneumonia who were hospitalised in the intensive care unit of a tertiary hospital in Guangdong province from April 2022 to August 2023 were selected and divided into the 6～<12 h group （T1 group，n=30），the 12～<16 h group （T2 group，n=30）， and the ≥16 h group （T3 group，n=30） according to the length of prone position ventilation.We observed and compared the oxygenation index， gastric residual volume and the occurrence of enteral nutrition⁃related complications，as well as the index changes of albumin and prealbumin in the three groups within 5 d after prone position.Results：The oxygenation status of all three groups of patients improved， and on the 4th and 5th day of ventilation， the improvement effect of T2 and T3 groups was better than that of T1 group （P<0.05）.The incidence of interruption and reflux complications was low in T1 and T2 groups， and albumin and prealbumin improved compared to before ventilation（P<0.05）..Conclusion：When the duration of prone ventilation in patients with severe pneumonia is 12～<16 h， it can effectively improve the oxygenation status and nutritional status of the patients with a lower complication rate.

Keywords    severe pneumonia； mechanical ventilation； prone position； duration； enteral nutrition； complications； oxygenation index

摘要  目的：探讨俯卧位通气持续时长对重症肺炎病人早期氧合及肠内营养安全性和有效性的影响。（剩余12427字）