结肠镜肠道准备质量受检者影响因素的Meta分析

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Abstract  Objective：To systematically evaluate the individual factors of colonoscopy bowel preparation quality.Methods：Studies on influencing factors of colonoscopy bowel preparation quality were searched from PubMed，EMbase，Web of Science，the Cochrane Library，ScienceDirect，CBM，CNKI，VIP and WanFang Database.The retrieval time was from inception to 31 October，2022.Two researchers independently screened the literature according to inclusion and exclusion criteria，and carried out quality evaluation and data extraction.RevMan 5.4 software was used for Meta⁃analysis.Results：A total of 22 studies were included.Meta-analysis results showed that：males had lower colonoscopy bowel preparation quality than females［OR=1.33，95%CI（1.16，1.53），P<0.000 1］，people with chronic constipation had lower colonoscopy bowel preparation quality than people without chronic constipation［OR=3.20，95%CI（1.80，5.67），P<0.000 1］，people with diabetes had lower colonoscopy bowel preparation quality than people without diabetes［OR=4.72，95%CI（2.18，10.22），P<0.000 1］，people taking opioids had lower colonoscopy bowel preparation quality than people not taking opioids［OR=1.60，95%CI（1.12，2.27），P=0.009］，people intaking high⁃fiber meals had lower colonoscopy bowel preparation quality than people not taking high⁃fiber meals［OR=2.94，95%CI（1.65，5.22），P=0.000 3］，people failed to finish taking the laxative had lower colonoscopy bowel preparation quality than people completely taking the laxative［OR=4.59，95%CI（3.45，6.10），P<0.000 1］，people underwent colonoscopy with an interval time longer than five hours after finishing laxative had lower colonoscopy bowel preparation quality than people underwent colonoscopy within five hours［OR=2.82，95%CI（1.79，4.45），P<0.000 1］，people without clean⁃water⁃like last stool had lower colonoscopy bowel preparation quality than people with clean⁃water⁃like last stool［OR=4.78，95%CI（2.35，9.71），P<0.000 1］.Conclusions：Current evidence showed that male，with chronic constipation，with diabetes，opioids use，a high⁃fiber diet before examination，inadequate intake of colon cleaning agent，the interval between the last does and the examination longer than five hours，the characteristics of last stool before colonoscopy was liquid with residue are individual risk factors for colonoscopy bowel preparation quality.

Keywords    colonoscopy； bowel preparation quality； influencing factors； Meta⁃analysis； evidence⁃based nursing

摘要  目的：系统评价结肠镜影响肠道准备质量的受检者因素。（剩余16037字）