地榆的研究进展及其质量标志物的预测分析

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中图分类号：R282.71 文献标志码：A 文章编号：1003-9783（2025）09-1603-12

doi：10.19378/j.issn.1003-9783.2025.09.019

Research Progress on Sanguisorbae Radix and Predictive Analysis of Its Quality Markers

REN Mengyang，YANG Meng’en，YANG Linfei，BAIMing，MIAO Mingsan （Academy of Chinese Medical Sciences， Henan Universityof Chinese Medicine/Henan Colaborative Innovation Center for Researchand Developmenton the Whole Chain of Yu-Yao，Henan University of Chinese Medicine，Zhengzhou 45O046 Henan，China）

Abstract：Sanguisorbae Radix exhibits diversepharmacological effects，including hemostatic，antibacterial，antiinflammatory，antioxidant，andantitumoractivities.Itisclinicallyused to treat hemorrhagicdisorders，burns，scalds， and enteritis.Its primarychemicalconstituents encompass tannins，triterpenoids，flavonoids，lignans，andorganic acids.This review systematically summarizes thechemical composition and pharmacological effects of Sanguisorbae Radix.Basedon the QualityMarker（Q-marker）theory of traditional Chinese medicine，it predicts potential Q-markers for Sanguisorbae Radix by evaluating seven key aspects：（1） chemicalcomposition and procesing methods，（2）plant phylogenetics，（3）therapeutic functions，（4） traditional eficacy and properties，（5）compatibility environments， （6） measurability，and（7）novel pharmacologicaleffects.Theanalysis suggests thattannins（galicacid，elagic acid， methyl gallate， procyanidins，and 3， 3′ ， 4′ 1 o -trimethyl ellagic acid），triterpenoids（ziyglycoside I and I）， flavonoids （catechin，quercetin，and kaempferol），and organic acids（（ferulicacid）may serve as robust Q-markers for Sanguisorbae Radix.These findings provide a theoretical foundation for refining its quality evaluation system.

Keywords：Sanguisorbae Radix；quality markers（Q-markers）；chemical constituents；pharmacological effects

地榆为蔷薇科植物地榆SanguisorbaofficinalisL.或长叶地榆Sanguisorba officinalisL.var.longifolia（Bert.）YüetLi的干燥根，别名“猪人参”“血箭草”“黄瓜香”，多生于草原、草甸、山坡草地、灌丛、疏林下。（剩余18712字）