1例女性原发性尿道肠型腺癌病例报告:3次手术和39个月随访

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A case report of female primary enteric adenocarcinoma of the urethra: 3 surgeries and 39-month follow-up
MA Peili1 ,DAI Haitao1 ,ZHANG Zhong1 ,JI Guanghai² ,ZHOU Meiyuan³ ,PENG Changweil (1.Department of Urology,2. Department of Radiology,3.Department of Pathology,The First Afiliated Hospital of Yangtze University,Jingzhou 4340oO,China)
ABSTRACT:ObjectiveTo explore the clinical characteristics and treatment methods of female primary enteric adenocarcinoma of theurethra.MethodsThediagnosis andtreatmentofonecase werereported.Theorigin,etiology,imaging findings,iagnosis,treatment,and prognosis were discused incombination with relevant literature.ResultsThepatientis a 61-year-oldfemale,vsitedourhospitalduetovaginalodorcomplicated withurethralbleding for2months,andwas diagnosed with urethral adenocarcinoma after examination.She underwent partial urethral resection,urethral meatus shaping and temporary blader fistula surgery,withnegativeresection margins.However,local recurence occurred7 months aftersurgery. The patientwasreadmitedforascondtime,undergoig laparoscopictotalurethralresectionanteriorvaginal wallresction, bladder neck resection,nd permanent bladder fistulation,followedbychemotherapy.Atthel9th monthafterthe firstsurgery, the patientwasadmitedduetotumorrecurrence,andthethirdsurgeryconsistedof totalbladderanduterusresection,ileal neobladder,andperineal closure.Postoperativepathologyindicatedurethraladenocarcinomaoriginatingfromtheintestines. Duringthe39-month follow-up,the tumorrecurred twice.Norecurrenceor metastasis wasobservedafterthefinal total pelvic exenteration.ConclusionEnteric adenocarcinomaof theurethra is extremelyrare.Comprehensive treatment including surgery,radiotherapy,andchemotherapymayprolongsurvival,uttheoverallprognosis isoorrequiringlong-termfollow-up.
KEY WORDS: female; primary urethral carcinoma; enteric adenocarcinoma of the urethra
摘要:目的探讨女性原发性尿道肠型腺癌的临床特点和诊疗方法。(剩余6125字)