上尿路结石合并非酒精性脂肪肝患者的临床特征及危险因素分析

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ABSTRACT：ObjectiveTo explore the clinical characteristics and riskfactors of upper urinary tractstones complicated with non-alcoholicfattliverdisease（NAFLD），soastoprovidereferenceforthe preventionofthisdisease.MethodsTheclinical data of 58 NAFLDpatients undergoing surgical treatment inour hospital during Jan.2022 and Jul.2O23 were retrospectively analyzed.According to whether the patients were complicated with NAFLD，they were divided into the NAFLD group （ n=56 ） and non-NAFLD group （ n=102， ）. The general data，laboratory indexes and 24-h urinary metabolic indexes were compared betweenthe two groups，andtheriskfactors were analyzed withunivariate and multivariatelogistic regressionanalyses.Results Compared with the non NAFLD group，the NAFLD group had higher BMI [（28.17±4.17） N ′s.（24.11±3.72 ） P<0.001] ， blood uric acid ） μmol/L vs. （294.41±93.72 ） μmol/L P<0.001] ，and 24-h urinary oxalate level [（37.74± （204 15.00）mmol vs ：1.（27.73±15.27 ）mmol， P<0.001] . Multivariate logistic analysis showed that BMI （ OR=1.311 P<0.001⟩ ， 24-h urinary oxalate （ OR=1.046 P=0.004 ），and 24-h urinary magnesium （ OR=0.599 ， P=0.002 ）were the independent factors for NAFLD with upper urinary tract stones.ConclusionNAFLD complicated with upper urinary tract stones is significantly associated with high BMI，high 24-h urinary oxalate，and low 24-h urinary magnesium.

KEY WORDS：non-alcoholic fatty liver disease；upper urinary tract stone；metabolic syndrome；24-h urinary metabolism摘要：目的探讨上尿路结石合并非酒精性脂肪肝（NAFLD）患者的临床特征及危险因素，为结石的预防提供参考。（剩余6670字）