一体位机器人辅助腹腔镜与后腹腔镜肾输尿管切除术治疗上尿路尿路上皮癌的疗效比较

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ABSTRACT：ObjectiveTo explore the clinical safety and efficacy of a single-position robot-assisted radical nephroureterectomy （RRUN） in the treatment of upper tract urothelial carcinoma （UTUC）.MethodsA retrospective study was conducted on 136 UTUC patients who underwent RRUN （n=35） and  laparoscopic radical nephroureterectomy （LRUN，n=101） in our hospital during Dec.2020 and Aug.2023.The perioperative and safety indicators of the two groups were compared.The intravesical recurrence-free survival （IVRFS），recurrence-free survival （RFS），and overall survival （OS） of the two groups were compared using Kaplan-Meier method.ResultsThere were no significant differences in the baseline data between the two groups （P>0.05）.All surgeries were successfully completed without conversion to open surgery.RRUN demonstrated superior perioperative outcomes compared to LRUN in overall postoperative complication rate [37.1%（13/35） vs. 56.4%（57/101）]，postoperative hospital stay [6（5，7） days vs. 7（6，8） days]，and catheter indwelling time [3（2，4）  days vs. 4（3，5）days]，with statistically significant differences （P<0.05）.Safety indicators of both surgical approaches were similar （P>0.05）.Survival analysisshowed no significant difference in oncological outcomes between the two groups [IVRFS （1 year：92.1%，2 years：85.2%），RFS （1 year：82.4%，2 years：74.9%），OS （1 year：90.6%，2 years：84.2%）] （P>0.05）.Conclusion Compared with retroperitoneal LRUN，single-position RRUN for UTUC demonstrates comparable safety and oncological efficacy，while offeringsignificant advantages in perioperative outcomes such as reducing postoperative complication rate and shortening hospitalstay.

摘要：目的探讨一体位机器人辅助腹腔镜肾输尿管切除术治疗上尿路尿路上皮癌（UTUC）的临床安全性和疗效。（剩余10329字）