智能控温控压输尿管软镜联合负压吸引鞘治疗直径≤2.5 cm上尿路结石的疗效分析

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ABSTRACT：ObjectiveTo investigate the efficacy and safety of intelligent temperature-pressure-controlled flexible ureteroscopy combined with negative-pressure suction sheath lithotripsy in the treatment of upper urinary tract stones ≤2.5 cm.MethodsThe clinical data of 225 patients with ≤2.5 cm upper urinary tract stones treated with this surgical method in our department during Aug. 2023 and Jul. 2024 were retrospectively analyzed. The patients were divided into the dual-control group （n=36） and conventional group （n=189） according to whether or not the intelligent temperature and pressure control device was used during operation. In the dual-control group，the intraoperative temperature and pressure in the renal pelvis were monitored and controlled in real time by the temperature and pressure sensors distributed at the end of the ureteral soft lens. The perioperative parameters，stone-removal rate，complication rate and renal function were compared between the two groups.ResultsAll operations were successfully completed in both groups. The postoperative procalcitonin （PCT） level [（22.75±5.85） ng/L vs. （29.08±6.60） ng/L，P=0.001]，difference in the white blood cell （WBC） level [（0.24±2.12）×109cells/L vs. （1.19±2.17）×109cells/L，P=0.016]，incidence of fever （2.8% vs. 16.9%，P=0.028） and overall complication rate （5.6% vs. 19.6%，P=0.042） were significantly lower in the dual-control group than in the conventional group，while the stone-clearance rate was slightly higher （88.9% vs. 82.5%，P=0.346），with no significant difference.ConclusionFor upper urinary tract stones ≤2.5 cm，intelligent temperature-pressure-controlled ureteroscopy combined with negative-pressure suction sheath lithotripsy has a satisfactory stone-removal rate and a low rate of complications，which is worthy of clinical promotion.

摘要：目的探讨智能控温控压输尿管软镜联合负压吸引鞘碎石术治疗直径≤2.5 cm上尿路结石的有效性和安全性。（剩余7878字）