某三甲医院下呼吸道标本耐碳青霉烯类鲍曼不动杆菌流行特点及耐药性分析

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中图分类号：R978 文献标志码：A 文章编号：1001-8751（2025）02-0126-05

Prevalence and Drug Resistance of Carbapenem-resistant Acinetobacter baumannii Isolated from Lower Respiratory Tract of a Tertiary Hospital

Liang Qiong，Li Su-yan （AdministratioepmtofocoalietecatedspialoagdicalUsity）

Abstract： Objective The prevalence and drug resistance of carbapenem-resistant Acinetobacter baumanni（CRAB） isolated from lower respiratory tract specimens were analyzed.MethodsRetrospective analysis of the clinical distribution characteristics and resistance to common antibiotics of CRAB in lower respiratory tract samples submited by hospitalized patients in a tertiary hospital from 2020 to 2022.ResultsFrom 2020 to 2022， 475 strains of CRAB were isolated from lower respiratory tract specimens of hospitalized patients，withthe highest detectionrateofCRABfromICU （60.42%） .Themedianageofpatientswas59 yearsold，andtheratioof maleto female was 3.1：1. With the exception of colistin， minocycline，and tigecycline， CRAB exhibited over 90% resistance tothe majorityofroutinelyusedantibiotics.There was no significant diference intheresistancerateofCRAB to most antibiotics in diferent areas.ConclusionDoctors should focus on the prudent use of antibiotics because the CRAB detection rate in lower respiratory tract specimens was high and the antimicrobial resistance was severe.

Key words： lower respiratory tract； carbapenem-resistant Acinetobacter baumanni； drug resistance： antimicrobial susceptibility testing； antibiotics

多重耐药菌的临床治疗日益困难，业已成为21世纪全球性公共卫生问题之一。（剩余6408字）