细菌耐药机理及应对策略

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中图分类号：R978 文献标志码：A 文章编号：1001-8751（2025）02-0107-09

The Mechanism of Bacterial Resistance and Human Response Strategies

YuanGuang-ying，WangMeng-long，YuXiao-lan，WangFang-jun （ZhejiangDeende Pharmaceutical Co.，Ltd， Shaoxing Zhejiang ）

Abstract：Antimicrobial medications have proliferated since the discovery of penicilin， which has caused humans to develop a resistance to bacterial illesses.At the same time，dueto their own genetic mechanisms and the abuse of antibacterial drugs，bacteria are forced to selective pressure and evolve drug resistance has made many antibacterial drugs lose their antibacterial efect.This article adopts research methods such as literature review， historical research，and case analysis to studyand analyze the various resistance mechanisms of bacteria against different antibacterial mechanisms，the existing problems related to bacterial resistance，and the posible causes of drug resistance.Multi-angle response strategies are suggested inan efort to shift the balance of the war between humans and bacteria in favor of humanitybased ontheanalysis of the factors influencing drug resistance response. These strategies aim to lesen the occurrence of bacterial resistance，particularly multi-resistance， while still eing effectively antibacterial.This is a significant event that deserves the attentionof allhumanity with significant theoretical and practical significance.

Key words： bacterial resistance；the mechanism of bacterial resistance；super bacteria；reasons for drug resistance； new antibacterial drugs； strategies for coping with bacterial resistance

自从英国科学家费莱明发现了青霉素，人类开启了抵抗细菌性感染的历史[。（剩余16040字）