脑电峰频率在慢性意识障碍中评估的应用现状及进展

Abstract：Thepeak frequency ofelectroencephalography（EEG）isamethod for inferring thalamocortical functional integrity basedon EEG dynamics.The ABCDmodel derived from this frequencycanindirectlyreflect patient'sconsciousness state，aiding in clinical asssment and prognosis prediction.Thisreview discusses the theoretical basis，application progress，and future challengesand directionsof EEGpeak frequency inthediagnosis and treatment of patientswith disorders of consciousness（DoC）.TheEEG peak frequency refers the strongest frequencypoint withina specific frequency band intheEEG signal，which reflects thecharacteristicsofcortical neural activity.Based on thespectral peaks inthe EEG power spectrum，itisclassified in ABCD four distinct models according the presence or absence of spontaneous neural oscilations，enabling more accurate clinical staging of patients with prolonged disorder of consciousness（pDoC）and aiding in prognosis evaluation and treatment guidance.Despitechallngessuch as limitedunderstanding of theunderlying mechanisms and the lack of definitive clinical evidence，EEG peak frequency has demonstrated significant potential inthe diagnosis and treatmenf pDo.

Key words：peak frequency of electroencephalography；prolonged disorder of consciousness；assessment; invasiveneuromodulation

脑电峰频率是脑电图信号中特定频段内最强的频率点，反映了大脑皮层神经活动的自发性、节律性特点[1]。（剩余13393字）