荧光素钠在胶质瘤术中应用的研究进展

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【中图分类号】 R739.41 【文献标志码】 A 【文章编号】 1672-7770（2025）03-0334-06

Abstract： This review examines the recent application sodium fluorescein（ SF） in glioma surgery， encompassing a thorough assessment itspractical performance，including the underlying principle， mechanism，intraoperative usage，clinical efectiveness，safety during surgery，and cost-effectiveness analysis SF.SF-guided glioma resection has the potential to markedly extend patient survival and enhancequality life through the intraoperativeadministration SF，facilitating thedelineation tumor boundariesand the precise excision tumor tissue.This method iscost-effctive，straightforward，andsafe，therebysignificantly enhancing tumor visualization.The purpose thisarticleis toprovideareference fortheapplication SFin glioma surgery.

Key words：glioma；sodium fluorescein；intraoperative navigation；amputate

胶质瘤是中枢神经系统最常见的原发性恶性肿瘤，其发病率和死亡率较高，高级别胶质瘤（high-gradeglioma，HGG）的平均生存周期只有 12～18 个月[1]。（剩余16654字）