安宁疗护理念下破解终末期患者参与临床试验困境的建议

[关键词]安宁疗护；终末期受试者；临床试验

[中图分类号]R-052 [文献标志码]A [文章编号]1001-8565（2025）07-0924-05

DOI：10.12026/j. issn.1001-8565.2025.07.17

Abstract： Palliative care is recognized as an effctive measure to improve the quality of life for patients with end-stage diseases，and the significance and role of such patients participating in clinical trials to conquer major diseases has also become a broad consensus.However，due to the special physical，psychological，and social conditions of terminal trial participants，the ethical problems encountered in the trial processare more serious and complex. Drawing on ethical practice experience，these seemingly common phenomena and issues were deeply analyzed. Combined with the palliative care philosophy for end-stage patients，this paper proposed a series of improvement suggestions throughout the entire life cycle of clinical trials，hoping to promote the quality improvement of clinical research in which end-stage patients participateas subjects，while effectively protecting the safety and rights of the subjects and ensuring they receive appropriate palliative care during their participation in clinical trialsorclinical-related scientific research.

Keywords： palliative care;end-stage patients；clinical trials

尽管人类寿命在不断延长，但是生病甚至病故几乎是每个人都无法避免的自然现象，既要通过医学科学研究努力攻克不治之症，又要实现人类在不治之症面前能够有尊严地度过生命的最后时光。（剩余7326字）