多层螺旋CT引导下肺活检穿刺在肺部病变良恶性鉴别诊断中的应用价值

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【Abstract】 Objective To explore the application value multi-slice spiral CT （MSCT） guided lung biopsy puncturein the diferential diagnosis benign and malignant lung lesions.MethodsSeventy-six patients with lung lesions whovisitedour hospital from July2O2Oto August 2O23 were includedas thestudy subjects.All patients underwent chest MSCT examination and lung biopsy guided by MSCT.The results chest MSCT examination，the results and successrate lung biopsy guided by MSCT，the detection complications inthe diagnosis benign and malignant lung lesions by chest MSCT guided lung biopsy，and the influencing factors on the occurrence postoperative complications after MSCT guided lung biopsy were analyzed.ResultsAll76 patients completed MSCTguided lung biopsyand puncture examinations.Pathological examination after puncture confirmed 58 cases with malignant lesions and18 cases with benign lesions in the lungs.One-time successul puncture was performed in 70 cases， with a success rate 92% . Six cases were successfully punctured twice， with a success rate 8% . After MSCTguided lung biopsy，there were5cases with local minor bleeding，11 cases with pneumothorax，and 3cases with pulmonaryinfection.The detectionrate patients withcomplications aged 6O years or older was higherthan that patients without complications，the average diameter lesions was smallr than that patients without complications， andthe distance between lesions andthe chest wallwas greater than that patients without complications，with statistical differences （ P <0.05）.Logistic regression analysis showed that patient age，lesion diameter，and distance between thelesion and chest wall were independent risk factors for theoccurrence postoperativecomplications after MSCTguided lung biopsy（ P<0.05） .ConclusionMSCT-guided lung biopsy can effectively differentiate benign and malignant lung lesions，improve thesuccessrateone-timepuncture lesions，reduce theriskcomplications after puncture，be safe and reliable，and have high promotion and application value.

【Key Words】Pulmonary lesions;Multi slice spiral CT guided lung biopsy puncture;Complication; Influence factor

肺部占位性病变临床诊断难度较高，由于症状不典型且呈多样性，特别是对于肺部微小病灶，临床诊断难度较高，但因肺部恶性病变病情进展速度较快，预后较差，为改善患者预后、延长生存时间，尽早明确肺部病变良恶性诊断显得尤为重要[1，2]。（剩余6000字）