非奈利酮临床应用研究进展

Clinical Application of Finerenone

WANG Shipeng,FU Qiuyu,LIU Jianxiong,HU Yongmei (DepartmentofCardiology,WestChinaSchoolofMedicine,Sichuan University,SichuanUniversityAfliatedChengdu Second People's Hospital,Chengdu Second People's Hospital,Chengdu 61O017,Sichuan,China)

【Abstract】Mineralocorticoidreceptorantagonist,spirolactoneandeplerenonearestronglyrecommendedinthetreatmentofheart failure,oweerutalaucddeactiotidsefalocoicdsts limitedFineeteodalcodtagstcdetyrte chronic kidneydisease.Thisarticlereviewstheaplicationoffinerenoneinthetreatmentofcardiovascularandrelateddiseases.

【Keywords】Finerenone;Nonsteroidal mineralocorticoid receptorantagonist;Cardiovascular-kidney-metabolic syndrome

心血管疾病、慢性肾脏病（chronic kidney disease，CKD)和代谢综合征［如2型糖尿病（type2diabetesmellitus，T2DM)]是威胁人类健康的三大慢性疾病，这三者不仅在流行病学上表现出高度重叠性，而且具有共同的病理生理机制[1-3]。（剩余11842字）