血液非靶向代谢组学在研究脊髓损伤后膀胱功能改变的可行性分析

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【中图分类号】R3【文献标志码】A【收稿日期】2025-01-22

Feasibility of blood untargeted metabolomics in studying bladder function changes after spinal cord injury

Kang Yinbo，Shuang Weibing （Department of Urology，The First Hospital of Shanxi Medical University）

【AbstractTraumaticspinalcordinjuryandbladderinjuryarebothcommonsurgicalinjuries.Metabolomicssudiesarethequalitative andquantitativeanalysisofallmetabolitesinaspecificpartoftheorgaismandthescienceoftechanginglawsofthesemtaboits underexternalinfluencsordseaseconditions.Thetechnologyismailytoanalyzthemetabolitesinbodyfuids，els，ndissus， andhasbecomeoneof theimportantmeansfordiscoveringbiomarkers.Thepsyhopathologyofspinalcordinjuryisverycomplex. Bloodmetabolomicsalowsdiferentialanalysisofthesubstancesinblodandhasgreatvalueforexploringthediseaseproesand mechanism.

【Keywords】blood metabolomics;spinal cord injury;bladder injury;biomarkers

脊髓损伤（spinalcord injury，SCI），是由于创伤或非创伤因素导致脊髓受损，引发结构或功能上的损害，是中枢神经系统中的1种严重疾病。（剩余15491字）