肺结节良恶性诊断中动态增强磁共振成像定量分析的 应用价值

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Exploring the application value of dynamic-enhanced magnetic resonance imaging quantitative analysis in thediagnosisof benignand malignant lungnodules

Li Yan， Guo Yangyang， Zhou Qing theFirstAffiliatedHospitalofHenanUniversity，Kaifeng475ooo，China

【Abstract】ObjectiveTo explore the application value of quantitative analysis of dynamic-enhanced magneticresonance imaging（DCE-MRI）in thediagnosis of benignand malignant diagnosis of lung nodules. MethodsA total of92 patientswith lung noduleswhounderwentCTand DCE-MRI from January2023 to December 2O23 were retrospectively analyzed in our hospital，and allpatientsunderwent puncture pathology biopsy after undergoing CT and DCE-MRI.The benign and malignant nature of the lung nodules of the patients wasconfirmed with the results of puncture pathology biopsy，and the diagnostic value of DCE-MRI for the diagnosisof benign and malignant lung nodules.ResultsTheresults of pathological testing showed that there were 49 cases of benign and 43 cases of malignant;thequantitative analysis parameters of DCE-MRI such as Ktrans，Kep，Ve，and Vp of malignant nodules were greater than those of benign nodules （ P <0.05）; theAUCs for diagnosis of distinguishing benign and malignant lung nodules by Ktrans，Kep，Ve，and Vp were O.779，0.792， 0.726 and O.657，respectively.The results showed that DCE-MRI had a higher sensitivity of 95.4% （41/43）， specificity of 98.0% （48/49），accuracy 96.7 % （89/92） than CT test of 79.1%（34/43），79.6% （39/49），and 79.4% （73/ 92） P<0.05） . ConclusionDCE-MRI quantitative analysis can effectively diagnose the benign and malignant lung nodules，and Ktrans and Kep values also havecertain diagnostic value for benign and malignant lung nodules.

【Key Words】 Multiple pulmonary nodules；Carcinoma；Magnetic resonance imaging；DiagnosisDOI：10.19522/j.cnki.1671-5098.2025.02.008

肺结节是一种临床上较为常见的疾病，其成因主要涵盖感染、炎症反应、免疫功能紊乱以及肺部组织结构变化等多种因素。（剩余6510字）