芪苈强心胶囊联合常规西药治疗慢性心力衰竭合并心房颤动疗效及安全性的Meta分析

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AbstractObjective：ToevaluatetheeficacyandsafetyQiiQiangxinCapsuleintreatingchronicheartfailurecombinedwitharial fibrilation.ethods：ClanFanDataBubedebfienceohanebrarndbseereafor randomizedcotroledialsC）withQiQiangiapsulesintreatmentoniceartlurcombedwithatrialfilatioi thesearchperiodrangingfrominceptiontoMarch2024.Literaturewasscreenedaccordingtoinclusionandexclusioncriteria.Review Manager5.4wasusedforMeta-analysis.Resuts：Atotal1320caseswereinvolvedinthisMeta-analysis，with66Ocasesineach group.resultstheMeta-analysisshowedthat Qi QiangxinCapsuleswithconventionalregimens inpatientswithchronicheart failureandatrial fibrillationimprovedthetotalclinicaleffectiverate（ RR=1.22 ， 95%C1 1.17-1.28， P<0.000 01），leftventricular ejection fraction（LVEF）（ MD=5.52 95%C1 4.26-6.77， P=0.34 ），reduced leftventricularend-systolicdiameter（LVESD）（ MD=-5.99 ， （204号 95%001-7.36-4.61 P<0.000 01 ），left ventricular end-diastolic diameter（LVEDD）（MD 1=-6.68 ，95%Cl-8.55--4.80， P<0.000 01 》 N-terminal B-type natriuretic peptide precursor（NT-proBNP）（SMD =-3.93 ，95%Cl-5.39--2.48， P<0.000 01 ），and QT dispersion （QTd） L MD=-6.28 95%C1 —6.99--5.57， P<0.000 1）.Conclusion：Existing evidence suggests that the combination Qili Qiangxin Capsules withconventialatmntanimproetalinptintsioicartflueomditrlfiiloiot seriousadverse reactions.However，the conclusion needs to be verified by more high-quality research.

sywordschronic heart failure;atrial fibrillation;Qili Qiangxin Capsule;Meta-analysis

慢性心力衰竭（chronicheartfailure，CHF）是各种心脏疾病的终末阶段，指由任何初始心肌损伤引起心脏结构或功能变化，导致心室泵血和（或）充盈功能低下的一种复杂的临床综合征[1]。（剩余10217字）