GCS评分、Rotterdam-CT评分联合血清SOD水平对不同程度颅脑损伤患者预后的应用价值

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Application value of GCS score， Rotterdam-CT score and serum SOD level in the prognosis of patients with different degrees of brain injury

CHEN Rut ⋅1 ， LIN Yongshuang'， LI Ziming 2 ， ZHU Yunzhong' ZHOU Qing'， ZHOU Haijing'，LU Shuanghong 1 ，HUANG Yi （20 （1.Department of Neurosurgery，the First Affiliated Hospital of Guangxi Universityof Traditional Chinese Medicine，Nanning 53oooo，Guangxi，China；2. School of Traditional ChineseMedicine， GuangxiHealth Vocational and TechnicalCollege，Nanning53oooo，Guangxi，China）

【Abstract】ObjectiveTo explore the aplication value of the Glasgow coma scale（GCS），Rotterdam-CT score combined with superoxide dismutase（SOD）levels inevaluating thedegreeof injuryand prognosis inpatients with traumatic braininjury（TBI）.Methods98patients with TBIadmited totheDepartmentof NeurosurgeryattheFirstAffliated Hospitalof Guangxi Universityof Traditional Chinese Medicinefrom March2O22to September2O23wereselected.Al patients were classfied into mild group，moderate group，andsevere groupaccording totheir GCS scores.Differences in SOD levelsandRoterdam-CTscoresamong patients withvaryingdegrees of injuryseveritywere compared，andcorrelation betweenthese twoindicatorsandtheseverityofTBIwasanalyzed.Univariateandmultivariateregressionanalyseswere conducted toidentifyindependentinfluencingfactorsforpoorprognosisinTBIpatients.Receiveroperatingcharacteristic （ROC）curve was used to analyse the evaluation value of GCS scores，Roterdam-CTscores，and SOD levels for por prognosis in TBI patients.Results ① There were statistically significant diferences in SOD levels and Rotterdam-CT scores among the three groups of patients （ P<0. 001 ）. ② Pearson correlation analysis showed that SOD levels were negatively corelatedwiththeseverityofTBI，whiletheRotterdam-CTscorewaspositivelycorrlatedwiththeseverityof TBI（ P< 0.001）. ③ The results of the ROC curve analysis showed that the area under the curve （ AUC ）for predicting the prognosis of TBI patientsbythe GCSscore，Rotterdam-CTscore，and SOD level aloneand in combination were O.879，0.873， 0.901，and0.959，respectively.ConclusionGCSscore，Roterdam CTscore，andSOD levelareclosely related to poor prognosis of TBI patients，andthecombination of the threeis more accurate in evaluating the prognosis of TBI patients.

【Keywords】traumatic brain injury；Glasgow coma score（GCS）； Rotterdam-CT score；superoxide dismutase（SOD）；damage degree;； prognosis

创伤性颅脑损伤（traumaticbrain injury，TBI）是由于头部受到外部机械应力而导致的暂时性或永久性脑功能损伤，是全球范围内所有年龄组人群死亡和残疾的主要原因之一[I]。（剩余6582字）