益生菌联合肠内营养对重症脑卒中病人胃肠道及感染性并发症影响的Meta分析

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AbstractOjective：Toevaluatethfectofprobioticscombedwithnteralutritioninterventioongastroitestinalandinfectios complications inpatientswith severestrokethroughMeta-analysis.Methods：RCTsontheefectsofprobioticscombined witheteral nutritionnterventionongastrointestinalandinfectiouscomplicationsinpatientswithseverestrokewereretrievedfrom Cochrane Library，PubMed，EMbase，CINAHL，WebofSience，CNKI，VIP，WanFangData.ProQuestandOpenGreywereretrievedtotain unpublishedresearch.TheretrievaldeadlinewasfromtheestablishmentofthedatabasetoMay31，2O24.TheCochraneCollaboration RoB2wasusedforliteraturequalityevaluation.Tworesearchers independentlyonductedliteraturesrening，dataextractio，and literaturequalityevaluationRevMan5.4softwarewasusedforMeta-analysis.Results：Atotalof2Oarticles were included，involving 1704 patientswithseverestroke.Metaanalysisresultsshowedthatprobioticscombiedwithenteralnutritioncanreducetheincidencef diarrhea（OR ∘eq 0.22，95%CI0.11-0.43， P<0.0001 ，bloating（OR ≡ 0.51，95%CI0.28-0.94 P=0.03， ，constipation（OR 0.44，95%CI0.22-0.89， P= 0.02），gastrointestinal bleeding（OR ∘eq 0.26， 95% CI 0.14-0.47， P<0.000 1），pulmonary infections（OR ∘eq 0.39，95%CI0.28-0.53， P< 0.000 01），urinary tract infections（OR=0.21，95%CI 0.13-0.35， P<0.000 O1），and gastrointestinal infections （OR=0.23，95%CI0.11-0.46，P< O.O1inpatietsitheverestroke.Coclusios：Existingevidencesuggeststhatproboticscombinedwithnteralnutrionintetio canreducetheincidenceofgstrontestinalcomplications（daeabloatig，onstipationgastroitestialbleding）andfectious complications（pulmonary infection，urinarytract infection，gastrointestinal infection）inpatientswithsevere stroke. Keywordsprobiotics;enteral nutrition; severe stroke;complications;Meta-analysis;evidence-based nursing

摘要目的：通过Meta分析方法评价益生菌联合肠内营养干预对重症脑卒中病人胃肠道及感染性并发症效果的影响。（剩余11989字）