不同清洁剂预防骨科外固定术后针道感染的网状Meta分析
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Different cleansing agents for prevention of pin site infection after orthopedic external fixation：a network Meta-analysis
Abstract Objective：This study evaluated the probability of different detergents in preventing pin tract infection after orthopedic external fixation by using network Meta-analysis.Methods：Using evidence-based search strategy，PubMed，Web of Science，MedLine，CINAHL，the Cochrane Library，EMbase，CNKI and WanFang Databases were searched by computer for clinical randomized controlled trials of detergent in preventing pin tract infection after orthopedic external fixation published from self-construction to April 30， 2023.The outcome measures were the incidence of pin tract infection and the positive rate of pin tract infection.The Cochrane risk of bias assessment tool was used to evaluate the quality of the included literatures.After the literature data were extracted，the RevMan 5.4 and Stata 17.0 software were used for data analysis. Results：Eight randomized controlled trials involving 439 patients with 4 435 pin sites were included.Of these，1 was a low risk study and 5 were medium risk studies.The results of network Meta-analysis showed that the infection rate of normal saline+1.5%H2O2+Xeroform（93.6%） and normal saline+Xeroform（70.6%） was higher than that of normal saline （62.0%）.The positive rate of infection was higher in normal saline+1.5% H2O2+Xeroform （91.2%），normal saline+0.2% polyhexamethylene biguanide（85.8%） and normal saline+Xeroform（53.2%） than in normal saline（52.7%）. Conclusion：Current evidence shows that normal saline+1.5%H2O2 +Xeroform is the most likely to be the best intervention in preventing the incidence of pin tract infection and infection positive rate after orthopedic external fixation among many detergents.
Keywords detergents; orthopedic external fixation; pin site infection; network Meta-analysis;randomized controlled trial; evidence-based nursing
摘要 目的：運用网状Meta分析方法评价不同清洁剂预防骨科外固定术后针道感染发生的概率。（剩余11907字）
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