非负重运动锻炼对糖尿病足溃疡病人影响的系统评价

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Abstract Objective：To systematically evaluate the effect of non-weight bearing exercise in patients with diabetes foot ulcer，and to provide evidence-based evidence for diabetes foot exercise intervention.Methods：The randomized controlled trials on the application of non weight bearing exercise in patients with diabetes foot ulcer were retrieved from PubMed，the Cochrane Library，EMbase，Web of Science，CNKI，WanFang Database.The search period was from the establishment of the database to August 31，2022.Literature screening，data extraction and literature quality evaluation were conducted by two researchers.RevMan 5.3 software was used for Meta-analysis.Results：A total of 15 randomized controlled trial articles were included，involving 1 296 diabetic foot patients.Meta-analysis showed that non-weight-bearing exercise could improve the wound healing rate［RR＝2.76，95％CI（2.00，3.80），P＜0.000 01］ and ABI［RR＝0.07，95％CI（0.04，0.10），P＜0.000 1］of diabetic foot ulcer patients.There was no significant difference in the incidence of adverse events during exercise between the two groups［RR＝0.76，95％CI（0.54，1.09），P＝0.14］.The effect of non-weight bearing exercise on blood glucose related indicators and quality of life was unclear.Conclusion：Available evidence suggests that non-weight bearing exercise has better clinical outcomes in diabetic foot ulcers，improves the rate of wound healing and improves ABI.The studies included in this study are limited in quality and quantity，so more high-quality and large-sample studies are needed to verify this conclusion.

Keywords diabetic foot ulcer;non-weight bearing exercise;wound healing rate;system evaluation;evidence-based nursing

摘要 目的：系统评价非负重运动锻炼在糖尿病足溃疡病人中应用效果，为糖尿病足运动干预提供循证依据。（剩余10325字）