调节肠道菌群治疗肠易激综合征的进展

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摘 要 肠易激综合征(IBS)是最常见的消化系统疾病之一,其特征是反复发作的腹痛和排便习惯改变。肠道微生态失衡在IBS发病机制中起到关键作用,进而通过不同方法调节肠道菌群是治疗IBS的重要方法。

关键词 肠易激综合征 益生菌 益生元 合生元 粪菌移植

中图分类号:R574.4 文献标志码:A 文章编号:1006-1533(2022)19-0023-05

引用本文 杨梅, 吕成娇, 张文成, 等. 调节肠道菌群治疗肠易激综合征的进展[J]. 上海医药, 2022, 43(19): 23-27.

基金项目:“十三五”重大专项子课题(2018ZX10732-202-004-005);国家科技支撑计划子课题(2015BAI13B08)

Progress of the regulation of intestinal flora in the treatment of irritable bowel syndrome

YANG Mei1, LYU Chengjiao2, ZHANG Wencheng1, RONG Yamei3

(1. Department of Gastroenterology, the Characteristic Medical Center of Chinese People’s Armed Police Force, Tianjin 300162, China; 2. Department of Gastroenterology, Central Hospital of Agricultural Reclamation Beian Administration Bureau, Heilongjiang Beian 164000, China; 3. Division of Gastroenterology, Tianjin Beichen Hospital, Tianjin 300400, China)

ABSTRACT Irritable bowel syndrome (IBS) is one of the most common digestive system diseases and is characterized by recurrent abdominal pain and changes in defecation habits. Intestinal microecological imbalance plays a key role in the pathogenesis of IBS, and then regulating intestinal flora by different methods becomes an important method for the treatment of IBS.

KEY WORDS irritable bowel syndrome; probiotics; prebiotics; synbiotics; fecal bacteria transplantation

肠道是包括细菌、古细菌、真菌、原生动物和病毒在内的数万亿微生物的居住地,其中鉴定出多达100属和1 000种不同的细菌[1]。(剩余11772字)

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