太赫兹光谱技术应用于艾绒中松油醇的检测

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中图分类号：O433.4文献标志码：A

Abstract： Moxa wool， renowned as a treasure trove of traditional Chinese medicine， harbors pharmacologically active constituents including terpineol， flavonoids， and terpenoids，among which terpineol exhibits notable anti-inflammatory and analgesic properties. Conventional chemical methodologies encounter technical challenges such as complex sample preparation， time-consuming analysis， and high costs in determining the content of terpineol in moxa wool. Instead， the use of terahertz spectroscopy for rapid and non-destructive detection of terpineol in moxa wool not only improves detection eficiency，but also offers advantages such as high sensitivity and simple operation.By comparing the characteristic peaks in terahertz spectra with the vibrational modes obtained from molecular simulations， qualitative detection of terpineol in moxa wool was achieved through "spectral fingerprints". Quantitative detection was accomplished through the peak area of characteristic peaks. After linear fitting using partial least squares （PLS） regression， the correlation coefficient between the predicted and actual terpineol contents reached 0.99. The research establishes a novel approach for quality authentication of moxa wool and offering fresh perspectives for quality assessment in traditional Chinese medicine.

Keywords： terpineol; moxa wool; terahertz; partial least squares method

艾叶为菊科蒿属多年生草本植物，其主要含有挥发油、黄酮类、萜类等成分，具有抗菌、镇痛、抗炎、抗氧化等多种药理作用[]。（剩余9431字）