铝涂覆层光纤前向受激布里渊散射对血液温度和 声阻抗的监测

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关键词：前向受激布里渊散射；铝涂覆层光纤;温度和声阻抗传感；血液监测;疾病诊断中图分类号：TN253 文献标识码：Adoi：10.37188/OPE.20253310.1534 CSTR：32169.14.OPE.20253310.1534

Monitoring of blood temperature and acoustic impedance based on forward stimulated brillouin scattering in aluminum coated optical fibers

HOU Shanglin*，SHAN Hang，DONG jie，WU Gang，YAN Zuyong （School ofScience，Lanzhou University of Technology，Lanzhou 73Oo5O，China） * Corresponding author， E -mail： houshanglin@vip.163. com

Abstract：Based on the temperature and acoustic impedance sensing theory utilizing forward stimulated Brillouin scattering（FSBS） in aluminum-coated optical fibers，the influence of coating thickness on acoustic mode frequency and linewidth was investigated，simultaneous measurement of temperature and acoustic impedance Was realized，and an innovative high-sensitivity method for disease detection in blood was proposed.The simulation results demonstrated linear relationships between the frequency/linewidth variations of radial acoustic modes R0，m with temperature and acoustic impedance. Fibers with different coating thicknesses exhibited distinct diferent sensitivities.The optimal linewidth-based acoustic impedance sensitivity is of 3.90MHz/（kg⋅mm2⋅s） at 3μm coating thickness and maximum frequency-based temperature sensitivity reaches up to 51.44kHz/∘C at 5μm coating thickness. Measurement errors can be reduced to 0.015∘C and 0.033kg/（mm2⋅s） for 3μm coating，and 0.008∘C and 0.027kg/（mm2⋅s） for 5μm coating，respectively.Taking ±0.5μm coating thickness variation into account， the temperature and acoustic impedance tolerance vary within 0.003-0.020∘C and 0.021-0.032kg/（mm2⋅s） for 3μm coating，and （20 0.003-0.009∘C with 0.004-0.058kg/（mm2⋅s） for 5μm coating，respectively. This sensing system enables real-time monitoring of blood temperature and acoustic impedance，demonstrating potential applications in distinguishing normal physiological states from pathological conditions （e.g.，hyperproteinemia， anemia）through multi-parameter analysis. The technology may provide innovative solutions for early disease diagnosis and precision medicine through its high-sensitivity detection capabilities.

Key words： Forward Stimulated Brillouin Scattering（FSBS）；aluminum-coated optical fiber； temperature and acoustic impedance sensing；blood monitoring；disease diagnosis

1引言

在现代生物医学领域，光纤传感技术在早期疾病诊断和实时监测中受到了广泛关注[1-3]。（剩余20767字）