高危和极高危局限性前列腺癌的治疗选择

ABSTRACT：In the treatment of high-risk and extremely high-risk localized prostate cancer，urologists，radiation therapists and oncologists have different opinions. With the development of new systemic therapy drugs and the application of genetic testing，treatment methods are constantly evolving. This article reviews the latest research progress，including radical prostatectomy，lymph node dissection，radiotherapy，and systemic treatment regimens （docetaxel-based therapy，novel endocrinotherapy，immunotherapy，targeted therapy），to systematically evaluate the long-term survival and tumor control efficacy of different treatment methods，so as to provide clinical reference.

摘要：关于高危和极高危局限性前列腺癌的治疗，泌尿外科、放疗科、肿瘤内科医生均有不同的见解。（剩余15820字）