经直肠双平面超声测量“角征”深度在直肠癌T分期中的临床价值

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ABSTRACTObjectiveTo measure the“angular sign”depth by transrectal biplane ultrasound,and to explore its clinicalvalueinT-stagingofrectalcancer.MethodsAtotalof33patientswithrectalcancerconfirmedbypostoperative pathology inourhospital were enrolled,including 11 patients with pathological stages pT1andpT2(lowT-stagegroup)and 22 patientswith stagespT3andpT4(highT-stage group).Transrectal biplaneultrasoundwasused toobtain tumorthickness, “angularsign”depth,distancefromthelowestboundaryoftherectaltumortotheanalverge,intra-tumoralbloodflowgrade,nd resistance index(RI).Thediferences inaboveultrasound examinationresults between the two groups werecompared.Receiver operatingcharacteristic((ROC)curves weredrawn toanalyzethediagnosticeficacyofultrasound examinationresultsforhigh T-stage rectalcancer.ResultsCompared with the low T-stage group,the high T-stage group exhibited increased tumor thickness and“angular sign”depth,with decreasedRI,the differences were statistically significant(all P <0.01).There were no significantdiferencesindistancefromhelowestboundaryoftherectaltumortotheanalverge,intratumoralbloodflowgrade between thetwo groups.ROC curve analysis showed thattheareaunder thecurves(AUC)for predicting high T-stage rectal cancer were0.907(95%CI:0.804-1.00)for“angularsign"depth,0.769(95%CI:0.579-0.958)fortumorthickness,and0.178 (95%CI:0.029-0.326) for RI.The“angular sign”depth demonstrated the highest AUC,with a sensitivity of 95.5% ,specificity of 63.6% ,and accuracy of 84.8% .Conclusion The“angular sign”depth measured by transrectal biplane ultrasound has certain clinical value in T-staging of rectal cancer.
KEYWORDSTransrectal biplane ultrasound;Rectal cancer;“Angular sign";T-staging
直肠癌是消化系统常见的恶性肿瘤,在消化系统新发恶性肿瘤病例中位居第三。(剩余6637字)