高频超声诊断老年肌少症的临床价值

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ABSTRACTObjectiveToinvestigate theclinical valueofhigh-frequencyultrasound inthediagnosis ofsarcopenia in geriatric patients.MethodsA total of 47 elderly aged ⩾ 60 years in Chengdu communities were enrolled and divided into sarcopenia( n =15)and non-sarcopenia( n =32)groupsbased on the 2O19 Asian Working Group for Sarcopenia(AWGS) criteria. High-frequencyultrasoundwasusedtomeasurethethickness,subcutaneousfattickness,rosssectionalreagrascaleof superficialflexoandrctufemoris,hicknes,ubcutaneusfatickness,rayscaleofretusabdominis,asellastcess andgrayscaleofanteriortibial muscle.Thediferences inabove parameters were compared betweenthetwogroups.Receiver operatingcharacteristic(ROC)curve was drawn to analyze the diagnostic eficacyoftheultrasound parameters fordiagnosing sarcopenia ingeriatric patients.ResultsCompared with the non-sarcopenia group,thesarcopenia group exhibited significantly reducedsubcutaneousfatthicknessoftherectusabdominisandincreasedgrayscaleofanteriortibialmuscle,thedierences were statistically significant(both P<0.05 ).There were no statistically significant differences in the thickness,subcutaneous fat thickness,crosetioalarascaleofpeficialflexorandtusbdomiis,icknss,aysaleofctusadois, wellasticknessofanterior tibialmuscle.ROCcurveanalysisshowedthattheareaunderthecurve(AUC)of thegrayscaleof anteriortibial musclefordiagnosingsarcopeniawasO.7O4,whichwas higherthanthatofsubcutaneous fatthicknessofrectus abdominis(O.315),the difference was statistically significant( P<0.05 ).The corresponding sensitivity and specificity were 66.7 % (20 and 75.0% ,respectively.ConclusionHigh-frequencyultrasound has acertain clinical value in the diagnosis of sarcopenia in geriatric patients.

KEYWORDsUltrasonography;Sarcopenia;Musclequality;Tibialis anterior grayscale;Rectusabdominis subcutaneous fat thickness

肌少症是一种以进行性骨骼肌质量下降和功能减退为特征的老年综合征,与跌倒风险增加、功能障碍及死亡率升高密切相关。(剩余6354字)

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