经颅彩色多普勒超声评估冠状动脉慢血流患者大脑中动脉血流动力学的临床价值

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ABSTRACTObjectiveToassess hemodynamicchanges middlecerebralartery（MCA）by transcranialcolor-code sonography（TCCS）inpatientswithcoronaryslowflow（CSF），andtoanalyzeitscorelationwiththrombolysis inmyocardial infarctionframecount（TFC）coronaryartery.MethodsAtotal1OOpatientsclinicallysuspectedcoronaryarterydisease admited todepartmentcardiologyinour hospital wereenroled，including55patients withCSF（CSFgroup）and 45 patients with normal coronary flow（NCF group）.TCCS was employed to measure MCA blood flow parameters in both groups， including peak systolic velocity（PSV），end-diastolic velocity（EDV），mean blood flow velocity（ ΔVmean ），resistance index（RI）， andpulsatilityde（P）.Additioalyteleftnteirdescendingartery，eftiumfleteryndigtorae weredetected bycoronaryangiography.Thecorelationsbetween hemodynamic parametersand TFCcoronaryarteryin patients with CSFwere analyzed.ResultsCompared withNCFgroup，PSV，EDV，Vmean，PI，andRIinCSFgroupwere decreased，whileCeftanteriordescendingartery，eftircumflexartery，ndightcoronaryarterywereincreased，ith statistically significant differences（all P<0.05 ）.Correlation analysis showed that ΔVmean and PSV were negatively correlated with TFC he leftanterior descending artery，left circumflex artery，and rightcoronary artery in patientswith CSF（all P<0.05 ） There wereno corelations between remaining hemodynamic parameters MCA with TFC coronaryartery.

ConclusionPatients withCSFexhibitabnoralhemodynamicsMCA，andseabormalitiesarenegativelycorrelatedwith TFC oronaryartery.TCCS has acertain clinicalvalue inassessng hemodyhamic changes MCA in patients with CSF.

KEYWORDsUltrasonography，Doppler，color，transcranial;Coronaryslowflow;Middlecerebralartery;Thrombolysis in myocardial infarction frame count;Hemodynamic

冠状动脉慢血流（coronaryslowflow，CSF）是指冠状动脉造影显示心外膜大血管无明显狭窄，但远端血流灌注延迟。（剩余8428字）