胃黏膜肠化生的风险分层和治疗策略

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Abstract Gastric intestinal metaplasia （GIM） represents a pivotal stage in the development of intestinal‐type gastric cancer. Classified as a gastric precancerous lesion， it significantly elevates the risk of gastric cancer. In particular， incomplete GIM and GIM at OLGIM stages Il to Ⅳ exhibit a higher risk of malignant transformation. Gastroscopic biopsy remains the gold standard for diagnosing GIM. Helicobacter pylori ‐ positive GIM patients should undergo eradication therapy， while certain drugs have demonstrated potential in reversing GIM. Regular gastroscopic surveillance of GIM may improve the detection rate of early gastric cancer. This article reviewed the risk stratification and treatment strategy for GIM.

Key words Gastric Intestinal Metaplasia; Risk Stratification; Therapy; Stomach Neoplasms

胃黏膜肠化生（gastric intestinal metaplasia， GIM）系指胃黏膜腺体被由杯状细胞、Paneth 细胞、吸收细胞等组成且能分泌黏液的肠黏膜腺体所取代的一种病理状态。（剩余14944字）