基于脉生痰核理论探讨中医药调控单核细胞分化、吞噬、积聚防治动脉粥样硬化

[关键词］动脉粥样硬化；脉生痰核；单核细胞；斑块

[中图分类号］R249 ［文献标志码］A [文章编号]0256-745（2025）09-079-04

DOl：0.3457/j.cnki.jncm.2025.09.033

Exploration of Prevention and Treatment of Atherosclerosis by Regulating Differentiation，Phagocytosis and Accumulation of Monocytes with Chinese Medicinals Based on Theory of Veins Generating Phlegm Node

QI Yuwen'，FANG Hui¹， ZENG Zhicong1，LIN Fengxia’，BAO Xiuzhen1，WU Wei²，SONG Yinzhi 1.The Seventh ClinicalMedicalScholofGuangzhouUniversityofChineseMedicine/ShenzhenBao'anTraditionalChineseMedicine Hospital，ShenzenGuangdong513，China；2.eFstAfliatedHspitalofGuangzouUiversityfCnesedicine，Guangzhou Guangdong 510405，China

Abstract：Atherosclerosis is the main cause of many cardiovascular diseases.In recent years，the incidence of atherosclerosis is graduall increased with thechanges of diet structureand liferhythms.As themain pathological product of atherosclerosis，restoring the normal structure and functionof blood vessels by plaques regression has beena major problem.The theoryof "veins generating phlegm node"forthe plaques hasbeen put forward in Chinese medicine， and the plaques are clasified into the categoryof "phlegm node"at macroscopic level，but the immune mechanismof monocytes in the process of plaques formation is not discussed in depth.Through the analogy of Chinese medicine thinking，the formationof "phlegmnode"is further related to the diferentiation，phagocytosis and accumulationof monocytes，and the mechanism of Chinese medicine in regressng plaques is explored so as to explore a new meting point for the prevention and treatment of atherosclerosis with Chinese medicine.

Keywords： Atherosclerosis；Veins generating phlegm node；Monocytes；Plaques

动脉粥样硬化（AS）是导致心血管疾病发生的首位原因。（剩余5791字）