我国心血管疾病患者用药偏差发生率及影响因素的Meta分析

打开文本图片集

【中图分类号】R473.5 【文献标识码】A

Meta-analysis of the prevalence and influencing factors of medication discrepanciesamongcardiovascular disease patients in China

ZHONG Xuelian， HE Wei， LI Jialu， GUO Hongxia

West China Hospital， Sichuan University/West China Schoolof Nursing， Sichuan University， Chengdu

，China

Corresponding author： GUO Hongxia， Email： guohongxia_99219@163.com

【Abstract】 Objective To systematically evaluate the incidence and influencing factors of medication discrepancies in patients with cardiovascular disease （CVD） in China. Methods CNKI，Wanfang，VIP，SinoMed，PubMed，Embase，Web ofScience，CINAHL，and the Cochrane Library databases were searched from their inception to December 2024.Literature on the incidence and influencing factors of medication discrepancies in patients with CVD in Chinese was included.Meta-analysis was performed using R4.3.2 software. Results A total of 22 articles were included， involving 6，278 patients.Meta-analysis results showed that the prevalence of medication discrepancies among Chinese CVD patientswas 67% [95%CI 0 56% 76% ].Highmonthlyhousehold income，high education level， good family functioning，living with others，fewer combined chronic diseases，a low Charlson comorbidity index，and male sex were protective factors for medication discrepancies，while a high number of medications used and the presence of adverse drug reactions were risk factors. Conclusion The prevalence of medication discrepancies among Chinese patients with CVD is high.Clinicians should identify high-risk patients based on these factors and conduct early screening and intervention to prevent medication discrepancies.

【Keywords】Cardiovascular diseases; Medication discrepancies; Incidence; Risk factors; Meta-analysis

心血管疾病（cardiovasculardisease，CVD）是对人类健康构成严重威胁的公共卫生问题，位居全球死因首位[。（剩余21250字）