长骨釉质瘤合并骨巨细胞瘤1例并文献复习

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Adamantinoma of long bones combined with giant cell tumor of bone： a case reportand literature review

ZHU Yali1， FAN Meng2，WU Juan1'， YANG Guifang1

1.Department of Pathology， Zhongnan Hospitalof Wuhan University，Wuhan 430o71，China

2. Department of Pathology，Wuxue Second People's Hospital，Huanggang 43540o，Hubei Province，

China

3.DepartmentofPathology，Zaoyang FirstPeople's Hospital， Xiangyang 4412oo，Hubei Province， China

Corresponding author： YANG Guifang， Email： YangGF@whu.edu.cn

【Abstract】 Adamantinoma of long bone （AD） and giant cell tumor of bone （GCTB） typically present as solitary bone lesions. It is extremely rare for both types of tumors to occur simultaneously inone patient.This article reports a17-year-old female patient who was admitted to the hospital due to right knee pain. Imagery suggested that the lower of the right femur and the upper of the right tibia had undergone bone destruction with the formation of soft tissue shadows. The clinicians diagnosed bone tumors and perform tumor curettage.The postoperative pathological diagnosis of the right femur lesion was GCTB，and the right tibia lesion was AD.The postoperative recovery was favorable，and no recurrence or metastasis so far. In this paper， we review the relevant literatures and summarize the clinical manifestations，imaging characteristics，pathomorphological features，andtreatmentmodalitiesofGCTBandAD.

【Keywords】Adamantinoma of long bones； Giant cell tumor of bone； Pathologic diagnosis； Bone tumors

长骨釉质瘤是一种罕见的具有上皮和间叶双相分化的骨肿瘤，好发于长骨{]。（剩余13020字）