能谱CT定量分析在甲状腺恶性结节诊断及颈部淋巴结转移评估中的应用

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中图分类号：R736.1，R445.9 文献标志码：A DOI：10.11958/20250052

Abstract： ObjectiveTo explore theapplication value of energy spectrum CTquantitative analysis in the diagnosis of malignantthyroid nodulesandevaluationofcervicallymphnode metastasis.MethodsAtotalof1O patients with thyroid nodules screened by ultrasound were selected as the study subjects.They were divided into the benign group （ n =42） and the malignant group （ n= 58）according to pathological results.Patients in the malignant group were sub-divided into the metastasis group （ n =26）and the non-metastasis group （ n =32）according to the presence or absence of cervical lymph node metastasis.Allpatientsreceivedenergyspectrum CTexamination.Theiodineconcentration （IC），normalizediodine concentration （NIC）and theslope of the spectral Hounsfield unit curve （入HU）were measured.The receiver operating characteristic （ROC）curve wasused to analyze theapplication value of energyspectrum CTquantitation in diagnosing malignant thyroid nodulesandevaluating cervical lymph node metastasis.ResultsThere were statisticallsignificant diferencesin CT features （shape，edge，cysticchangesand surrounding tisse invasion）between benign and malignant thyroid nodules （ P<0.05 ）.However，there were no statistically significant diferences in the maximum diameter，number， enhancement degree and calcification（ P>0.05 ） IClesion ，NICand λHU were lower in the benign group than those of the malignant group. IC ，NIC and 入HU of the metastasis group were lower than those of the non-metastasis group （ P<0.05 ） 1esion ROC curve analysis results showed that the AUCs，specificity，sensitivity and Youden index of the combination of 1Clesion. NIC andλHUfordiagnosing malignantthyroid nodulesand evaluatingcervicallymphnodemetastasis were higherthanthoseof each parameter （ P<0.05 ）. ConclusionEnergy spectrum CT quantitative analysis is of high value in the diagnosis of malignant thyroid nodules and evaluation of cervical lymph node metastasis.

Key Words： thyroid nodule; neck; lymphatic metastasis; energy spectrum CT quantitative analysis

目前甲状腺恶性结节发病率为 5%～10% ，对患者生命健康造成极大的威胁1。（剩余9845字）