探究血必净辅助治疗对重症肺炎患者白细胞计数血小板计数 氧合指数 降钙素原白细胞介素-6的作用

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Effectsof Xuebijing asisted therapy on white blood cell count，platelet count，oxygenation index， procalcitonin，and interleukin-6inseverepneumonia patientsJiangXi.

【Abstract】ObjectiveTo explore the effects of Xuebijing-assisted therapyon white blood cell count （WBC），plateletcount （PLT），oxygenationindex （PaO/FiO），procalcitonin （PCT），andinterleukin（IL）-6inpatients with severepneumonia.MethodsThe clinical data of 7O patientswithseverepneumonia from February 2022 to February 2O23 inour hospital were retrospectivelyanalyzed.According to the clinical treatment，theywere divided intoa reference group and a studygroup，with 35 cases in each group.Patients in the reference group received piperacillin/tazobactam，whilepatients in the studygroup received Xuebijing inaddition topiperacilln/tazobactam. Treatment effects，WBC，PLT， PaO2/FiO2 ，PCT，IL-6，IL-1O，vital signs indicators，Sequential Organ Failure Score （SOFA），Acute Physiological and Chronic Health Score （APACHE II），Clinical Pulmonary Infection Score （CPIS） were compared.ResultsPatientsin the study group hada higher responserate than the reference group（ P< 0.05）.WBC，PLC，serum PCT，IL-6，and IL-1O levels in the study group were lower than thosein the reference group，and PaO2/FiO2 were higher than those in the reference group （ P <0.05）.The temperature，pulse，and respiration in the study group were lower than those in the reference group（ P <0.05）. SOFA， APACHE II，and CPIS scores of patients in the study group were lower than those in the reference group （ P <0.05）. Conclusion Xuebijing combined with piperacilin/tazobactam treatment can effectively improve theclinical symptoms of patients with severepeumonia，stabilize the vital signs，adjust theserum index with PaO2/FiO2，andimprove the treatment response rate.

【Key words】Pneumonia；Critical care;Xuebijing;Oxygenation index；Procalcitonin；Clinical efficacy

重症肺炎是一种危害严重的急性呼吸道疾病其致命性和传染能力令人担忧。（剩余5846字）