振动强耦合的量子生物调控机制与应用前沿
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中图分类号：0437文献标志码：A
Vibrational strong coupling： frontiers in quantum biological regulatory mechanisms and applications
YUAN Ming'，WANG Xiaowei，LU Weiwei，ZHAO Xinmin （1. College of Chemistry and Life Science， Chifeng University， Chifeng O240oo， China; 2. Shandong Guoyuan Human Genetic Resource Bank Management Co.， Ltd.， Jinan 250101， China; 3.DepartmentofGeneral Practice，Xinhua Hospital Affiliatedto Shanghai Jiao Tong University School ofMedicine， Shanghai 200093， China; 4. School of Optical-Electrical and Computer Engineering， Universityof Shanghai for Science and Technology， Shanghai 200093，China）
Abstract： Vibrational strong coupling （VSC） involves the coupling of molecular vibrations with electromagnetic radiation in the mid-infrared or terahertz region. This coupling leads to the formation of new states， known as polaritons， which have unique properties that can be exploited for various applications. Over the past decade， significant progress has been made in manipulating chemical reactions using VSC. Placing biological reactions in an optical cavity allows for the hybridization of cavity modes with the energy of biological molecules， which can control biological reactions.However，the effect of the so-called "dark states"， which refer to the absence of external energy interference， on biological reactions is still a mystery. In biochemistry， VSC can be used to study the vibrational properties of biomolecules such as proteins and nucleic acids，which can provide insights into their structures and functions.Additionally， VSC can be used to manipulate and control the chemical reactions of these biomolecules， which has potential implications for drug development and other biomedical applications.This article provides an overview of VSC and its potential applications in biochemistry， including recent advances and future directions， with a focus on the experimental difficulties and potential for development of strong vibrational coupling in controlling biological reactions.
Keywords： vibrational strong coupling; Fabry-Perot cavity; enzymatic catalysis; Rabi splitting： polariton state;
量子电动力学（quantumelectrodynamics，QED）揭示了自发辐射（如荧光）与电磁场零点能之间的联系[1]。（剩余14640字）
