孤独在乳腺癌患者社会限制与抑郁间的中介效应

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中图分类号：R473.73 文献标志码：A

本文引用：．孤独在乳腺癌患者社会限制与抑郁间的中介效应[J]．医学研究与教育，2025，42（6）：50-56.DOI：10.3969/j.issn.1674-490X.2025.06.006.

文章编号：1674-490X（2025）06-0050-07

Mediating effect of loneliness between social constraints and depression in breast cancer patients

CAO Longnu， CUI Hongquan， WANG Yinling

（Department of Oncology，Suzhou Jiulong Hospital，School of Medicine，Shanghai Jiao Tong Universi-

ty，Suzhou ，China）

Abstract：Objective To investigate the mediating effect of lonelinesson the relationship between social constraints and depression in breast cancer patients and inform the reduction of the incidence of depression in breast cancer patients.Methods Data were collcted from 257 breast cancer patients at a hospital in Jiangsu province using three scales：the Patient Health Depresson Questionnaire，Social Constraints Scale，and Cancer Loneliness Scale. General information was then analyzed. Results Depression，social constraints and loneliness scores of breast cancer patients were 6.63±3.15 ， 30.71±7.73 （20 and 2 1.24±5.21 respectively. Depression was positively connected to social constraints and loneliness， and social constraints was positively connected to loneliness （ r=0.498 ， r=0.396 ， r=0.639 ，all P< 0.01）.The loneliness of breast cancer patients has a partial mediating efect between social constraints and depression，with the mediating effect making up 27.15% of the total effect. Conclusion Medical workers should take measures to reduce the social constraints of breast cancer patients and reduce the loneliness so as to reduce the occurrence of depression.

Key words： breast cancer; depression； social constraints； loneliness； mediating effect

乳腺癌是女性最常见的恶性肿瘤，也是女性癌性死亡的重要原因之一[1]。（剩余7242字）