仙茅的质量控制现状及质量标志物预测分析

ABSTRACTCurculigoorchioidesrefers tothedriedrhizomeofaplantfromAmarylldaceae familyandexhibitsavarietyof pharmacologicalactivitiessuchasanti-osteoporosis，anti-inflammatory，anti-oxidationandimmuneregulation.However，the current quality control of C .orchioides mainly relies on the determination of a single indicator component（curculigoside），which makes it diffculttoreflect itsqualityfully.Atthesametime，factorssuchas processing methods，harvestingtimes，andplaceof origins can also lead to variations in the types and contents of chemical constituents in C orchioides.Based on the theory of quality markers （Q-markers）for traditional Chinese medicine，a predictive analysis of the Q-markers of C .orchioides was conducted from sevenperspectives：plantphylogenyandspecificityofchemicalconstituents，tradionalmedicinalproperties，eicacyplaceof originandharvestingperiod，procesingmethods，measurabilityofchemicalconstituents，andblood-entryconstituents.Itis preliminarily speculated that curculigoside，sakakin，orcinol gentiobioside，curculigosideB，curlignan， β -sitosterol，actinidioionoside， 2，6-dimethoxybenzoicacid，curculigoside C，glucosyringic acid，orcinol and stigmasterol are Q-markers of C orchioides， providing a scientific basis for establishing a comprehensive and systematic quality evaluation system for C .orchioides.

KEYWORDS Curculigo orchioides；quality control;quality markers；prediction

仙茅为石蒜科植物仙茅CurculigoorchioidesGaertn.的干燥根茎，常于秋、冬二季采挖，经除根头和须根、洗净、干燥等工序后制得。（剩余8876字）