支持医保知证决策的降糖新药多维价值评估框架研究
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中图分类号R977.1+5 文献标志码A 文章编号1001-0408（2025）13-1563-05
DOI 10.6039/j.issn.1001-0408.2025.13.02
on the multi-dimensional value assessment framework new antidiabetic drugs to support evidence-inmed medical insurance decision-making
YAN Feifei1，CHEN Jingyu1，CHEN Jiaran1，PAN Chen1，WANG Guohua²，GENG Jinsongl（1. Inmatics， School of 226001，China;2.National Diseases， Hospital，Capital ，Beijing lOo053，China）
ABSTRACTOBJECTIVEToestablishamulti-dimensional valueassssentframework newantidiabeticdrugs basedon multi-criteriadecisionanalysistheorythusprovidingatheoreticalframeworkandmethodologyevidence-inmedmedical insurancedecision-making.METHODSFirstly，multi-dimensionalevidencewassearchedandobtainedtoprovidereliabledata theestablishmentoftheframework.Secondlyintersoftheobtainedevidence，thvalueassessmentframeworkwaspreliarily constructed.Itsstructure，maincorecriteria，andcontextualciteriaweredeterminedtrough focusgroupdiscussion.inally，the crieriaandsub-riteriaoftheframeworkandtheirweightswerefurtherdetermined，reasonsinclusionofsub-riteriaandthe reasonablenessofrating scores were evaluated，and methodsof assessment wereoptimized through expert consultation.REULTS Themulti-dimensionalvalueasessentframeworknewantidiabeticdrugswascomposedofcorecriteriaandcontextualized criteriawhichcouldbeusedquantitativeandqualitativevalueassessmentofnewdrugs，respectively.Thecorecriteria consistedoffivedimensions，withaffrdability（6.31）havingthehighestweightingscore，followedbycomparativeefectivenes （6.20），comparativesafety（6.01），cost-efectiveness（5.89），andqualityofevidence（5.46）.Afterthenormalizationof weight withinsub-criteria，the budgetimpactonmedicalinsurancehadthehigheststandardized weight，folowedbythecontrolof glycatedemoglobinandpatientadability.Thecontextualcriteriaincludedtwodimensions，i.e.，innovationandequity. CONCLUSIONSTheassessmentframework integratesevidence，stakeholders’values，anddecisioncontexts toenableamulidimensional and evidence-based assessment of the value of new antidiabetic drugs.
KEYWORDsnewantidiabeticdrugs；evidence-inmed decision-making；medical insurance；valueasessment framework; multi-criteria decision analysis
糖尿病是严重影响人民身体健康和生活质量的慢性非传染性疾病。（剩余9282字）
