全腔镜甲状腺癌根治术对甲状腺癌患者甲状腺功能及机体应激反应的影响

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摘 要 目的：探讨全腔镜甲状腺癌根治术在甲状腺癌（TC）患者治疗中的应用价值。方法：将76例TC患者随机分为对照组和研究组，各38例。对照组行传统开放手术，研究组行全腔镜甲状腺癌根治术。对比两组围术期指标、甲状腺功能、应激反应、并发症。结果：研究组手术时间、切口长度、术后住院时间短于对照组，术中出血量少于对照组，术后24 h视觉模拟量表评分，术后48 h三碘甲状腺原氨酸（T3）、游离T3、甲状腺素（T4）、游离T4及术后24 h血糖、皮质醇、肾上腺素水平，术后并发症发生率低于对照组，促甲状腺激素水平高于对照组（P

关键词 甲状腺癌 全腔镜甲状腺癌根治术 甲状腺功能 应激反应 并发症

中图分类号：R730.56； R736.1 文献标志码：B 文章编号：1006-1533（2023）05-0025-05

引用本文 杨明威， 张聪敏， 郭金培. 全腔镜甲状腺癌根治术对甲状腺癌患者甲状腺功能及机体应激反应的影响[J].上海医药， 2023， 44（5）： 25-29.

Effect of total endoscopic thyroidectomy on thyroid function and stress response in patients with thyroid cancer

YANG Mingwei， ZHANG Congmin， GUO Jinpei

（Department of General SurgeryⅡ， the Seventh People’s Hospital of Zhengzhou， Zhengzhou 450000， China）

ABSTRACT Objective： To explore the value of total endoscopic thyroidectomy in the treatment of thyroid cancer （TC）. Methods： Seventy-six patients with TC were randomly divided into a control group and a research group， with 38 cases each. The control group was treated with traditional open surgery， while the research group was treated with total endoscopic thyroidectomy. Perioperative indexes， thyroid function， stress response and complications were compared between the two groups. Results： The operation time， incision length and postoperative hospital stay were shorter， the intraoperative blood loss was less， 24 h postoperative visual analogue score， the levels of 48 h postoperative triiodothyronine （T3）， free T3， thyroxine （T4）， free T4 and 24 h postoperative glucose， cortisol， epinephrine and the incidence of postoperative complication were lower， and the levels of thyroid stimulating hormone were higher in the research group than the control group （P

KEY WORDS thyroid cancer； total endoscopic thyroidectomy； thyroid function； stress reaction； complication

甲状腺癌（thyroid carcinoma， TC）是头颈部常见恶性肿瘤，好发于女性群体，且随着年龄增大，TC发生风险增高[1]。（剩余5272字）