急性白血病患儿感染炎症因子、凝血指标、血小板参数结果分析

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【摘 要】目的:研究急性白血病(AL)感染患儿炎症因子、凝血指标及血小板参数检测的效果。方法:数据遴选我院2020年1月至2021年5月收治的80例AL患儿,根据“是否感染”分感染组(感染,n=30),参照组(未感染,n=50),对其炎症因子、凝血指标及血小板参数进行检测,两组检测结果比较。结果:与参照组比较,感染组CRP、PT、APTT及FIB指标更高,PLT指标更低,MPV、PDW及P-LCR指标更高,具有统计学意义(P
【关键词】急性白血病;感染;炎症因子;凝血指标;血小板参数
Analysis of inflammatory factors, coagulation indexes and platelet parameters in children with acute leukemia
XU Chunyan1, WU Baoze2, BIAN Xingyan1
1. Dalian women’s and children’s Medical Center (Group), Dalian, Liaoning 116044, China;
2. Dalian Medical University, Dalian, Liaoning 116044, China
【Abstract】Objective: To study the effect of inflammatory factors, coagulation indexes and platelet parameters in children with acute leukemia (AL) infection. Methods: 80 children with AL treated in our hospital from January 2020 to May 2021 were selected. They were divided into infection group (infection, n=30) and reference group (uninfected, n=50) according to "infection or not". The inflammatory factors, coagulation indexes and platelet parameters were detected. The results of the two groups were compared. Results: Compared with the reference group, the indexes of CRP, PT, APTT and FIB in the infection group were higher,the indexes of PLT in the infection group were lower, the indexes of MPV, PDW and P-LCR in the infection group were higher(P
【Key?Words】Acute leukemia; Infected; Inflammatory factors; Coagulation index; Platelet parameters
临床较常见血液系统病症为急性白血病(AL),患病时骨髓中幼稚细胞、原始细胞大量增殖、对正常造血产生抑制,广泛浸润淋巴结、肝脏等器官,导致患儿呈高热、贫血、骨关节疼痛及淋巴结肿大等表现,分析病因尚未明,可能与遗传、病毒及电离辐射等因素有关,患病后若未及时提供对症治疗,则危及生命。(剩余2520字)