阳虚证大鼠模型的制备方法研究进展
〔摘要〕 阳虚证是中医临床中常见的证候,阳气虚衰会引起很多临床疾病,因此,建立系统的阳虚证大鼠模型造模方法对临床疾病的研究具有重要的意义。按照中医脏腑辨证,将阳虚证分为心阳虚、脾阳虚、肾阳虚、肺阳虚、脾肾阳虚、心肾阳虚,对其造模方法进行论述,为中医临床相关疾病的实验研究提供参考。
〔关键词〕 阳虚证;大鼠模型;造模方法;脏腑辨证;评价标准
〔中图分类号〕R25 〔文献标志码〕B 〔文章编号〕doi:10.3969/j.issn.1674-070X.2022.09.025
Research progress in the preparation method of rat models of Yang deficiency syndrome
REN Yuting GUO Wanqin WANG Yuqing XIAO Hongbin NIU Wenying LI Fengjin
(1. Heilongjiang University of Chinese Medicine, Harbin, Heilongjiang 150040, China;
2. Heilongjiang Academy of Traditional Chinese Medicine, Harbin, Heilongjiang 150036, China)
〔Abstract〕 Yang deficiency syndrome is common in traditional Chinese medicine (TCM) clinic. Deficiency of Yang Qi causes many clinical diseases. Therefore, a systematicmodeling method of rat model with Yang deficiency is significant. According to the syndrome differentiation of Zang and Fu organs, the Yang deficiency syndrome is divided into heart Yang deficiency, spleen Yang deficiency, kidney Yang deficiency, lung Yang deficiency, spleen and kidney Yang deficiency, heart and kidney Yang deficiency. The modeling methods are discussed, which can provide reference for the experimental research of clinical related diseases in TCM.
〔Keywords〕 Yang deficiency syndrome; rat models; modeling method; syndrome differentiation of Zang and Fu organs; evaluation criteria
阳虚是中医病机概念,是指机体阳气不足,温煦功能减退,不能抵御阴寒之气表现出的证候,临床特征表现有畏寒、肢冷、口淡不渴、喜热饮、自汗、面色㿠白、尿少不利、大便稀薄、舌淡胖、苔白滑、脉沉无力等。(剩余9909字)