造血干细胞移植病人疲乏现状及影响因素

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· 科研论著 ·

作者简介 李佳帅，硕士研究生在读

通讯作者 刘树佳，E⁃mail：15546132940@163.com

引用信息 李佳帅，刘树佳，胡伟.造血干细胞移植病人疲乏现状及影响因素[J].护理研究，2024，38（1）：67⁃74.

Study on fatigue and its influencing factors in patients with hematopoietic stem cell transplantation

LI Jiashuai， LIU Shujia， HU Wei

School of Nursing， Peking University， Beijing 100191 China

Corresponding Author  LIU Shujia， E⁃mail： 15546132940@163.com

Abstract  Objective：To investigate the status quo of fatigue in patients with hematopoietic stem cell transplantation （HSCT） and analyze its influencing factors， so as to provide references for formulating targeted intervention measures for fatigue in patients with HSCT.Methods：217 HSCT patients who were followed up in the inpatient department or outpatient department of 9 tertiary grade A hospitals in Beijing from September 2019 to March 2020 were investigated with Self⁃Designed General Data Questionnaire， Revised Piper Fatigue Scale， Hospital Anxiety and Depression Scale， International Physical Activity Questionnaire， Exercise Self⁃Efficacy Scale and Social Support Rating Scale.Results：Among 217 HSCT patients，131 patients （60.37%） had no fatigue， 27 patients （12.44%） had mild fatigue， 49 patients （22.58%） had moderate fatigue， and 10 patients （4.61%） had severe fatigue. Ordered Logistic regression analysis showed that anxiety， physical activity intensity， exercise self⁃efficacy and transplant times were the influencing factors of fatigue in HSCT patients （P<0.05）.Conclusion：Although the fatigue of HSCT patients has been improved， it is still not optimistic. It is suggested that various measures should be implemented according to the influencing factors to reduce the fatigue level of patients and improve their quality of life.

Keywords    hematopoietic stem cell transplantation， HSCT； fatigue； anxiety； depression； physical activity； exercise self⁃efficacy；social support； influencing factors

摘要  目的：调查造血干细胞移植（HSCT）病人疲乏现况并分析其影响因素，为制定HSCT病人疲乏的针对性干预措施提供参考。（剩余16751字）