氧化应激与炎症性肠病

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Oxidative StressandInflammatory BowelDiseaseLI Hanyu’，SHDongyun²，ZHENGSongbai'.'Departmentof GastroenterologyHudongHositalfliatedtdnUesitynghai（o）;eprtmentofhestrd Moleculariology，SchoolofasicedicalSciences，FudanUniversity，hnghai

Correspondence to：ZHENG Songbai，Email： songbai10o9@163.com

AbstractInflammatory bowel disease （IBD），agroupof chronic non-specific gastrointestinal inflammatorydisorders， hasshownanupward trend inglobal incidence.However，thepathogenesisofIBDremains elusive，andthetherapeutic effctsarefrequentlyfarfromsatisfactory，significantlycompromising thequalityof lifeof patients.Inrecentyears， research onthe association between oxidative stressandIBD has drawn substantial atention，which mayunveil novel therapeutic targets for IBD.This article reviewed the relationship between oxidative stress and IBD.

KeyWordsInflammatory Bowel Disease;CrohnDisease；Colitis，Ulcerative;Oxidative Stress

炎症性肠病（inflammatoryboweldisease，IBD）是一组慢性非特异性胃肠道炎性疾病，包括溃疡性结肠炎（ulcerativecolitis，UC）和克罗恩病（Crohn'sdisease，CD），其临床表现除腹痛、腹泻、便血等肠道症状外，还有发热、疲乏等全身表现以及关节、皮肤、黏膜、肝胆等肠外损害。（剩余20071字）